VD phys represents the overall ventilatory efficiency, including circulatory dynamics, and a total of ventilation/perfusion ( ) mismatch. However, serum cytokine levels are affected not only by the ventilator setting, but also by duration, surgical invasion, bleeding, and any stress to the patient. However, another randomized controlled study reported no differences between the lung-protective properties of PC-IRV and volume-control ventilation (VCV) when performed for >2 h in robot-assisted laparoscopic radical prostatectomy, as determined by the changes in serum cytokine levels. We believe that PC-IRV might be a lung-protective ventilation strategy. Some apparatus dead space may actually reduce total dead space, as an ETT bypasses the majority of anatomical dead space of the patient (nasopharynx).ĭead space from the patient.Previously, we studied the changes in dead space components within a short duration (30 min) of each ventilator mode using a cross-over study design, and reported that pressure-controlled inverse ratio ventilation (PC-IRV) reduces the physiological dead space (VD phys). Types of Dead Spaceĭead space from equipment, such as tubes ventilator circuitry. Glomerular Filtration and Tubular Functionĭead space is the proportion of minute ventilation which does not participate in gas exchange. Functional Anatomy and Control of Blood Flow
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